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Characterization of Rett Syndrome-like phenotypes in Mecp2-knockout rats
BACKGROUND: Rett Syndrome (RTT) is a neurodevelopmental disease caused by the disruption of the MECP2 gene. Several mouse models of RTT have been developed with Mecp2 disruptions. Although the mouse models are widely used in RTT research, results obtained need to be validated in other species. There...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910223/ https://www.ncbi.nlm.nih.gov/pubmed/27313794 http://dx.doi.org/10.1186/s11689-016-9156-7 |