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Characterization of Rett Syndrome-like phenotypes in Mecp2-knockout rats

BACKGROUND: Rett Syndrome (RTT) is a neurodevelopmental disease caused by the disruption of the MECP2 gene. Several mouse models of RTT have been developed with Mecp2 disruptions. Although the mouse models are widely used in RTT research, results obtained need to be validated in other species. There...

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Detalles Bibliográficos
Autores principales: Wu, Yang, Zhong, Weiwei, Cui, Ningren, Johnson, Christopher M., Xing, Hao, Zhang, Shuang, Jiang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910223/
https://www.ncbi.nlm.nih.gov/pubmed/27313794
http://dx.doi.org/10.1186/s11689-016-9156-7