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Hedgehog pathway is involved in nitidine chloride induced inhibition of epithelial-mesenchymal transition and cancer stem cells-like properties in breast cancer cells

BACKGROUND: The complications of clinical metastatic disease are responsible for the majority of breast cancer related deaths, and fewer therapies substantially prolong survival. Nitidine chloride (NC), a natural polyphenolic compound, has been shown to exhibit potent anticancer effects in many canc...

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Detalles Bibliográficos
Autores principales: Sun, Mingjuan, Zhang, Ning, Wang, Xiaolong, Li, Yaming, Qi, Wenwen, Zhang, Hanwen, Li, Zengjun, Yang, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910241/
https://www.ncbi.nlm.nih.gov/pubmed/27313840
http://dx.doi.org/10.1186/s13578-016-0104-8