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ATRX immunostaining predicts IDH and H3F3A status in gliomas

Gliomas are the most frequent intraaxial CNS neoplasms with a heterogeneous molecular background. Recent studies on diffuse gliomas have shown frequent alterations in the genes involved in chromatin remodelling pathways such as α-thalassemia/mental-retardation-syndrome-X-linked gene (ATRX). Yet, the...

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Detalles Bibliográficos
Autores principales: Ebrahimi, Azadeh, Skardelly, Marco, Bonzheim, Irina, Ott, Ines, Mühleisen, Helmut, Eckert, Franziska, Tabatabai, Ghazaleh, Schittenhelm, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910252/
https://www.ncbi.nlm.nih.gov/pubmed/27311324
http://dx.doi.org/10.1186/s40478-016-0331-6