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Reconstitution of immune cell in liver and lymph node of adult- and newborn-engrafted humanized mice
BACKGROUND: Humanized mouse models are an increasingly popular preclinical model to study the human immune response in a biological system. There are a variety of protocols to generate these mice, each differing in the strain of the recipient, source of hematopoietic stem cells, and mode of transpla...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910253/ https://www.ncbi.nlm.nih.gov/pubmed/27307066 http://dx.doi.org/10.1186/s12865-016-0157-9 |