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IgE-mediated enhancement of CD4(+) T cell responses requires antigen presentation by CD8α(−) conventional dendritic cells

IgE, forming an immune complex with small proteins, can enhance the specific antibody and CD4(+) T cell responses in vivo. The effects require the presence of CD23 (Fcε-receptor II)(+) B cells, which capture IgE-complexed antigens (Ag) in the circulation and transport them to splenic B cell follicle...

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Detalles Bibliográficos
Autores principales: Ding, Zhoujie, Dahlin, Joakim S., Xu, Hui, Heyman, Birgitta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910288/
https://www.ncbi.nlm.nih.gov/pubmed/27306570
http://dx.doi.org/10.1038/srep28290