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IgE-mediated enhancement of CD4(+) T cell responses requires antigen presentation by CD8α(−) conventional dendritic cells
IgE, forming an immune complex with small proteins, can enhance the specific antibody and CD4(+) T cell responses in vivo. The effects require the presence of CD23 (Fcε-receptor II)(+) B cells, which capture IgE-complexed antigens (Ag) in the circulation and transport them to splenic B cell follicle...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910288/ https://www.ncbi.nlm.nih.gov/pubmed/27306570 http://dx.doi.org/10.1038/srep28290 |