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B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation
BACKGROUND: A diverse B-cell repertoire is essential for recognition and response to infectious and vaccine antigens. High-throughput sequencing of B-cell receptor (BCR) genes can now be used to study the B-cell repertoire at great depth and may shed more light on B-cell responses than conventional...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910312/ https://www.ncbi.nlm.nih.gov/pubmed/27312086 http://dx.doi.org/10.1186/s13073-016-0322-z |