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B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation

BACKGROUND: A diverse B-cell repertoire is essential for recognition and response to infectious and vaccine antigens. High-throughput sequencing of B-cell receptor (BCR) genes can now be used to study the B-cell repertoire at great depth and may shed more light on B-cell responses than conventional...

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Detalles Bibliográficos
Autores principales: Galson, Jacob D., Trück, Johannes, Clutterbuck, Elizabeth A., Fowler, Anna, Cerundolo, Vincenzo, Pollard, Andrew J., Lunter, Gerton, Kelly, Dominic F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910312/
https://www.ncbi.nlm.nih.gov/pubmed/27312086
http://dx.doi.org/10.1186/s13073-016-0322-z