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The Mineralocorticoid Agonist Fludrocortisone Promotes Survival and Proliferation of Adult Hippocampal Progenitors

Glucocorticoid receptor (GR) activation has been shown to reduce adult hippocampal progenitor cell proliferation and neurogenesis. By contrast, mineralocorticoid receptor (MR) signaling is associated with neuronal survival in the dentate gyrus of the hippocampus, and impairment of hippocampal MR has...

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Detalles Bibliográficos
Autores principales: Gesmundo, Iacopo, Villanova, Tania, Gargantini, Eleonora, Arvat, Emanuela, Ghigo, Ezio, Granata, Riccarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910464/
https://www.ncbi.nlm.nih.gov/pubmed/27379018
http://dx.doi.org/10.3389/fendo.2016.00066