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The Mineralocorticoid Agonist Fludrocortisone Promotes Survival and Proliferation of Adult Hippocampal Progenitors
Glucocorticoid receptor (GR) activation has been shown to reduce adult hippocampal progenitor cell proliferation and neurogenesis. By contrast, mineralocorticoid receptor (MR) signaling is associated with neuronal survival in the dentate gyrus of the hippocampus, and impairment of hippocampal MR has...
Autores principales: | Gesmundo, Iacopo, Villanova, Tania, Gargantini, Eleonora, Arvat, Emanuela, Ghigo, Ezio, Granata, Riccarda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910464/ https://www.ncbi.nlm.nih.gov/pubmed/27379018 http://dx.doi.org/10.3389/fendo.2016.00066 |
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