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Asiatic Acid Protects against Cardiac Hypertrophy through Activating AMPKα Signalling Pathway

Background: AMPactivated protein kinase α (AMPKα) is closely involved in the process of cardiac hypertrophy. Asiatic acid (AA), a pentacyclic triterpene, was found to activate AMPKα in our preliminary experiment. However, its effects on the development of cardiac hypertrophy remain unclear. The pres...

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Detalles Bibliográficos
Autores principales: Ma, Zhen-Guo, Dai, Jia, Wei, Wen-Ying, Zhang, Wen-Bin, Xu, Si-Chi, Liao, Hai-Han, Yang, Zheng, Tang, Qi-Zhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910604/
https://www.ncbi.nlm.nih.gov/pubmed/27313499
http://dx.doi.org/10.7150/ijbs.14213