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α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke

Human rhinovirus (HRV) infections target airway epithelium and are the leading cause of acute exacerbations of COPD. Cigarette smoke (CS) increases the severity of viral infections, but there is no effective therapy for HRV infection. We determined whether α1-antitrypsin (A1AT) reduces HRV-16 infect...

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Detalles Bibliográficos
Autores principales: Berman, Reena, Jiang, Di, Wu, Qun, Chu, Hong Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910614/
https://www.ncbi.nlm.nih.gov/pubmed/27354786
http://dx.doi.org/10.2147/COPD.S105717