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α1-Antitrypsin reduces rhinovirus infection in primary human airway epithelial cells exposed to cigarette smoke
Human rhinovirus (HRV) infections target airway epithelium and are the leading cause of acute exacerbations of COPD. Cigarette smoke (CS) increases the severity of viral infections, but there is no effective therapy for HRV infection. We determined whether α1-antitrypsin (A1AT) reduces HRV-16 infect...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910614/ https://www.ncbi.nlm.nih.gov/pubmed/27354786 http://dx.doi.org/10.2147/COPD.S105717 |