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The multidrug-resistance transporter Abcc3 protects NK cells from chemotherapy in a murine model of malignant glioma
Abcc3, a member of the ATP-binding cassette transporter superfamily, plays a role in multidrug resistance. Here, we found that Abcc3 is highly expressed in blood-derived NK cells but not in CD8(+) T cells. In GL261 glioma-bearing mice treated with the alkylating agent temozolomide (TMZ) for 5 d, an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910710/ https://www.ncbi.nlm.nih.gov/pubmed/27467914 http://dx.doi.org/10.1080/2162402X.2015.1108513 |