Combined inhibition of TGFβ and PDGF signaling attenuates radiation-induced pulmonary fibrosis

Background: Radiotherapy (RT) is a mainstay for the treatment of lung cancer, but the effective dose is often limited by the development of radiation-induced pneumonitis and pulmonary fibrosis. Transforming growth factor β (TGFβ) and platelet-derived growth factor (PDGF) play crucial roles in the de...

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Detalles Bibliográficos
Autores principales: Dadrich, Monika, Nicolay, Nils H., Flechsig, Paul, Bickelhaupt, Sebastian, Hoeltgen, Line, Roeder, Falk, Hauser, Kai, Tietz, Alexandra, Jenne, Jürgen, Lopez, Ramon, Roehrich, Manuel, Wirkner, Ute, Lahn, Michael, Huber, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910723/
https://www.ncbi.nlm.nih.gov/pubmed/27467922
http://dx.doi.org/10.1080/2162402X.2015.1123366

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910723/
https://www.ncbi.nlm.nih.gov/pubmed/27467922
http://dx.doi.org/10.1080/2162402X.2015.1123366

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