Prothymosin-α Variants Elicit Anti-HIV-1 Response via TLR4 Dependent and Independent Pathways

BACKGROUND: Prothymosin α (ProTα) (isoform 2: iso2) is a widely distributed, small acidic protein with intracellular and extracellular-associated functions. Recently, we identified two new ProTα variants with potent anti-HIV activity from CD8(+) T cells and cervicovaginal lavage. The first is a spli...

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Detalles Bibliográficos
Autores principales: Gusella, G. Luca, Teixeira, Avelino, Aberg, Judith, Uversky, Vladimir N., Mosoian, Arevik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910978/
https://www.ncbi.nlm.nih.gov/pubmed/27310139
http://dx.doi.org/10.1371/journal.pone.0156486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910978/
https://www.ncbi.nlm.nih.gov/pubmed/27310139
http://dx.doi.org/10.1371/journal.pone.0156486

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