Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents

The synthesis of novel phosphatidylcholines with geranic and citronellic acids in sn-1 and sn-2 positions is described. The structured phospholipids were obtained in high yields (59–87%) and evaluated in vitro for their cytotoxic activity against several cancer cell lines of different origin: MV4-11...

Descripción completa

Detalles Bibliográficos
Autores principales: Gliszczyńska, Anna, Niezgoda, Natalia, Gładkowski, Witold, Czarnecka, Marta, Świtalska, Marta, Wietrzyk, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911001/
https://www.ncbi.nlm.nih.gov/pubmed/27310666
http://dx.doi.org/10.1371/journal.pone.0157278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911001/
https://www.ncbi.nlm.nih.gov/pubmed/27310666
http://dx.doi.org/10.1371/journal.pone.0157278

Ejemplares similares