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Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents
The synthesis of novel phosphatidylcholines with geranic and citronellic acids in sn-1 and sn-2 positions is described. The structured phospholipids were obtained in high yields (59–87%) and evaluated in vitro for their cytotoxic activity against several cancer cell lines of different origin: MV4-11...
Autores principales: | Gliszczyńska, Anna, Niezgoda, Natalia, Gładkowski, Witold, Czarnecka, Marta, Świtalska, Marta, Wietrzyk, Joanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911001/ https://www.ncbi.nlm.nih.gov/pubmed/27310666 http://dx.doi.org/10.1371/journal.pone.0157278 |
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