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Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

Triple-negative breast cancer (TNBC) is a heterogeneous disease that can be classified into distinct molecular subtypes by gene expression profiling. Considered a difficult-to-treat cancer, a fraction of TNBC patients benefit significantly from neoadjuvant chemotherapy and have far better overall su...

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Detalles Bibliográficos
Autores principales: Lehmann, Brian D., Jovanović, Bojana, Chen, Xi, Estrada, Monica V., Johnson, Kimberly N., Shyr, Yu, Moses, Harold L., Sanders, Melinda E., Pietenpol, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911051/
https://www.ncbi.nlm.nih.gov/pubmed/27310713
http://dx.doi.org/10.1371/journal.pone.0157368