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Association of Hepatitis B Virus Covalently Closed Circular DNA and Human APOBEC3B in Hepatitis B Virus-Related Hepatocellular Carcinoma

Chronic Hepatitis B Virus (HBV) infections can progresses to liver cirrhosis and hepatocellular carcinoma (HCC). The HBV covalently-closed circular DNA cccDNA is a key to HBV persistence, and its degradation can be induced by the cellular deaminase APOBEC3. This study aimed to measure the distributi...

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Detalles Bibliográficos
Autores principales: Luo, Xuan, Huang, Yao, Chen, Yanmeng, Tu, Zeng, Hu, Jieli, Tavis, John E., Huang, Ailong, Hu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911053/
https://www.ncbi.nlm.nih.gov/pubmed/27310677
http://dx.doi.org/10.1371/journal.pone.0157708