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Analysis of Chemokine Receptor Trafficking by Site-Specific Biotinylation

Chemokine receptors undergo internalization and desensitization in response to ligand activation. Internalized receptors are either preferentially directed towards recycling pathways (e.g. CCR5) or sorted for proteasomal degradation (e.g. CXCR4). Here we describe a method for the analysis of recepto...

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Detalles Bibliográficos
Autores principales: Liebick, Marcel, Schläger, Christian, Oppermann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911081/
https://www.ncbi.nlm.nih.gov/pubmed/27310579
http://dx.doi.org/10.1371/journal.pone.0157502