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A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis

BACKGROUND: Periodontitis is characterized by microbial infection, inflammation, tissue breakdown, and accelerated loss of alveolar bone matrix. Treatment targeting these multiple stages of the disease provides ways to treat or prevent periodontitis. Certain glycosaminoglycans (GAGs) block multiple...

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Detalles Bibliográficos
Autores principales: Savage, Justin R., Pulsipher, Abigail, Rao, Narayanam V., Kennedy, Thomas P., Prestwich, Glenn D., Ryan, Maria E., Lee, Won Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911086/
https://www.ncbi.nlm.nih.gov/pubmed/27308827
http://dx.doi.org/10.1371/journal.pone.0157310