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A Modified Glycosaminoglycan, GM-0111, Inhibits Molecular Signaling Involved in Periodontitis
BACKGROUND: Periodontitis is characterized by microbial infection, inflammation, tissue breakdown, and accelerated loss of alveolar bone matrix. Treatment targeting these multiple stages of the disease provides ways to treat or prevent periodontitis. Certain glycosaminoglycans (GAGs) block multiple...
Autores principales: | Savage, Justin R., Pulsipher, Abigail, Rao, Narayanam V., Kennedy, Thomas P., Prestwich, Glenn D., Ryan, Maria E., Lee, Won Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911086/ https://www.ncbi.nlm.nih.gov/pubmed/27308827 http://dx.doi.org/10.1371/journal.pone.0157310 |
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