Retinal Inhibition of CCR3 Induces Retinal Cell Death in a Murine Model of Choroidal Neovascularization

Inhibition of chemokine C-C motif receptor 3 (CCR3) signaling has been considered as treatment for neovascular age-related macular degeneration (AMD). However, CCR3 is expressed in neural retina from aged human donor eyes. Therefore, broad CCR3 inhibition may be harmful to the retina. We assessed th...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Han, Xiaokun, Gambhir, Deeksha, Becker, Silke, Kunz, Eric, Liu, Angelina Jingtong, Hartnett, M. Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911089/
https://www.ncbi.nlm.nih.gov/pubmed/27309355
http://dx.doi.org/10.1371/journal.pone.0157748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911089/
https://www.ncbi.nlm.nih.gov/pubmed/27309355
http://dx.doi.org/10.1371/journal.pone.0157748

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