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Retinal Inhibition of CCR3 Induces Retinal Cell Death in a Murine Model of Choroidal Neovascularization
Inhibition of chemokine C-C motif receptor 3 (CCR3) signaling has been considered as treatment for neovascular age-related macular degeneration (AMD). However, CCR3 is expressed in neural retina from aged human donor eyes. Therefore, broad CCR3 inhibition may be harmful to the retina. We assessed th...
Autores principales: | Wang, Haibo, Han, Xiaokun, Gambhir, Deeksha, Becker, Silke, Kunz, Eric, Liu, Angelina Jingtong, Hartnett, M. Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911089/ https://www.ncbi.nlm.nih.gov/pubmed/27309355 http://dx.doi.org/10.1371/journal.pone.0157748 |
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