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Predicted Coverage and Immuno-Safety of a Recombinant C-Repeat Region Based Streptococcus pyogenes Vaccine Candidate

The C-terminal region of the M-protein of Streptococcus pyogenes is a major target for vaccine development. The major feature is the C-repeat region, consisting of 35–42 amino acid repeat units that display high but not perfect identity. SV1 is a S. pyogenes vaccine candidate that incorporates five...

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Detalles Bibliográficos
Autores principales: McNeilly, Celia, Cosh, Samantha, Vu, Therese, Nichols, Jemma, Henningham, Anna, Hofmann, Andreas, Fane, Anne, Smeesters, Pierre R., Rush, Catherine M., Hafner, Louise M., Ketheesan, Natkuman, Sriprakash, Kadaba S., McMillan, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911098/
https://www.ncbi.nlm.nih.gov/pubmed/27310707
http://dx.doi.org/10.1371/journal.pone.0156639