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Thiophenone Attenuates Enteropathogenic Escherichia coli O103:H2 Virulence by Interfering with AI-2 Signaling

Interference with bacterial quorum sensing communication provides an anti-virulence strategy to control pathogenic bacteria. Here, using the Enteropathogenic E. coli (EPEC) O103:H2, we showed for the first time that thiophenone TF101 reduced expression of lsrB; the gene encoding the AI-2 receptor. C...

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Detalles Bibliográficos
Autores principales: Witsø, Ingun Lund, Valen Rukke, Håkon, Benneche, Tore, Aamdal Scheie, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911109/
https://www.ncbi.nlm.nih.gov/pubmed/27309855
http://dx.doi.org/10.1371/journal.pone.0157334