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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis

Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influences integration...

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Detalles Bibliográficos
Autores principales: Campos-Sánchez, Rebeca, Cremona, Marzia A., Pini, Alessia, Chiaromonte, Francesca, Makova, Kateryna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911145/
https://www.ncbi.nlm.nih.gov/pubmed/27309962
http://dx.doi.org/10.1371/journal.pcbi.1004956