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Integration and Fixation Preferences of Human and Mouse Endogenous Retroviruses Uncovered with Functional Data Analysis
Endogenous retroviruses (ERVs), the remnants of retroviral infections in the germ line, occupy ~8% and ~10% of the human and mouse genomes, respectively, and affect their structure, evolution, and function. Yet we still have a limited understanding of how the genomic landscape influences integration...
Autores principales: | Campos-Sánchez, Rebeca, Cremona, Marzia A., Pini, Alessia, Chiaromonte, Francesca, Makova, Kateryna D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911145/ https://www.ncbi.nlm.nih.gov/pubmed/27309962 http://dx.doi.org/10.1371/journal.pcbi.1004956 |
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