Statins Inhibit Fibrillary β-Amyloid Induced Inflammation in a Model of the Human Blood Brain Barrier

BACKGROUND: Astrocytes and cerebral endothelial cells are important components of the blood-brain barrier (BBB). Disruption to this barrier through inflammation is a major contributor to Alzheimer’s disease (AD) pathology. The amyloid beta (Aβ) protein is known to exist in several forms and is a key...

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Detalles Bibliográficos
Autores principales: Griffin, Jarred M., Kho, Dan, Graham, E. Scott, Nicholson, Louise F. B., O’Carroll, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911157/
https://www.ncbi.nlm.nih.gov/pubmed/27309956
http://dx.doi.org/10.1371/journal.pone.0157483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911157/
https://www.ncbi.nlm.nih.gov/pubmed/27309956
http://dx.doi.org/10.1371/journal.pone.0157483

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