KSP inhibitor SB743921 induces death of multiple myeloma cells via inhibition of the NF-κB signaling pathway

SB743921 is a potent inhibitor of the spindle protein kinesin and is being investigated in ongoing clinical trials for the treatment of myeloma. However, little is known about the molecular events underlying the induction of cell death in multiple myeloma (MM) by SB743921, alone or in combination tr...

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Detalles Bibliográficos
Autores principales: Song, In-Sung, Jeong, Yu Jeong, Nyamaa, Bayalagmaa, Jeong, Seung Hun, Kim, Hyoung Kyu, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911184/
https://www.ncbi.nlm.nih.gov/pubmed/25772758
http://dx.doi.org/10.5483/BMBRep.2015.48.10.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911184/
https://www.ncbi.nlm.nih.gov/pubmed/25772758
http://dx.doi.org/10.5483/BMBRep.2015.48.10.015

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