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KSP inhibitor SB743921 induces death of multiple myeloma cells via inhibition of the NF-κB signaling pathway
SB743921 is a potent inhibitor of the spindle protein kinesin and is being investigated in ongoing clinical trials for the treatment of myeloma. However, little is known about the molecular events underlying the induction of cell death in multiple myeloma (MM) by SB743921, alone or in combination tr...
Autores principales: | Song, In-Sung, Jeong, Yu Jeong, Nyamaa, Bayalagmaa, Jeong, Seung Hun, Kim, Hyoung Kyu, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911184/ https://www.ncbi.nlm.nih.gov/pubmed/25772758 http://dx.doi.org/10.5483/BMBRep.2015.48.10.015 |
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