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Implications of NQO1 in cancer therapy

NAD(P)H:quinone oxidoreductase (NQO1), an obligatory two-electron reductase, is a ubiquitous cytosolic enzyme that catalyzes the reduction of quinone substrates. The NQO1- mediated two-electron reduction of quinones can be either chemoprotection/detoxification or a chemotherapeutic response, dependi...

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Detalles Bibliográficos
Autores principales: Oh, Eun-Taex, Park, Heon Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911202/
https://www.ncbi.nlm.nih.gov/pubmed/26424559
http://dx.doi.org/10.5483/BMBRep.2015.48.11.190