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N-acetyl cysteine inhibits H(2)O(2)-mediated reduction in the mineralization of MC3T3-E1 cells by down-regulating Nrf2/HO-1 pathway

There are controversial findings regarding the roles of nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway on bone metabolism under oxidative stress. We investigated how Nrf2/HO-1 pathway affects osteoblast differentiation of MC3T3-E1 cells in response to hydrogen per...

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Detalles Bibliográficos
Autores principales: Lee, Daewoo, Kook, Sung-Ho, Ji, Hyeok, Lee, Seung-Ah, Choi, Ki-Choon, Lee, Kyung-Yeol, Lee, Jeong-Chae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911206/
https://www.ncbi.nlm.nih.gov/pubmed/26303969
http://dx.doi.org/10.5483/BMBRep.2015.48.11.112