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Concerted nucleophilic aromatic substitution with (19)F(−) and (18)F(−)
Nucleophilic aromatic substitution (S(N)Ar) is widely used by organic chemists to functionalize aromatic molecules, and it is the most commonly used method to generate arenes that contain a (18)F for use in PET imaging.(1) A wide range of nucleophiles exhibit S(N)Ar reactivity, and the operational s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911285/ https://www.ncbi.nlm.nih.gov/pubmed/27281221 http://dx.doi.org/10.1038/nature17667 |