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Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

Polymyxins, an old class of antibiotics, are currently used as the last resort for the treatment of multidrug-resistant (MDR) Acinetobacter baumannii. However, recent pharmacokinetic and pharmacodynamic data indicate that monotherapy can lead to the development of resistance. Novel approaches are ur...

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Detalles Bibliográficos
Autores principales: Tran, Thien B., Cheah, Soon-Ee, Yu, Heidi H., Bergen, Phillip J., Nation, Roger L., Creek, Darren J., Purcell, Anthony, Forrest, Alan, Doi, Yohei, Song, Jiangning, Velkov, Tony, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911330/
https://www.ncbi.nlm.nih.gov/pubmed/26669752
http://dx.doi.org/10.1038/ja.2015.127