Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach

New antimycotic drugs are challenging to find, as potential target proteins may have close human orthologs. We here focus on identifying metabolic targets that are critical for fungal growth and have minimal similarity to targets among human proteins. We compare and combine here: (I) direct metaboli...

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Detalles Bibliográficos
Autores principales: Kaltdorf, Martin, Srivastava, Mugdha, Gupta, Shishir K., Liang, Chunguang, Binder, Jasmin, Dietl, Anna-Maria, Meir, Zohar, Haas, Hubertus, Osherov, Nir, Krappmann, Sven, Dandekar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911368/
https://www.ncbi.nlm.nih.gov/pubmed/27379244
http://dx.doi.org/10.3389/fmolb.2016.00022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911368/
https://www.ncbi.nlm.nih.gov/pubmed/27379244
http://dx.doi.org/10.3389/fmolb.2016.00022

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