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Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network Approach
New antimycotic drugs are challenging to find, as potential target proteins may have close human orthologs. We here focus on identifying metabolic targets that are critical for fungal growth and have minimal similarity to targets among human proteins. We compare and combine here: (I) direct metaboli...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911368/ https://www.ncbi.nlm.nih.gov/pubmed/27379244 http://dx.doi.org/10.3389/fmolb.2016.00022 |