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Neurofilament depletion improves microtubule dynamics via modulation of Stat3/stathmin signaling

In neurons, microtubules form a dense array within axons, and the stability and function of this microtubule network is modulated by neurofilaments. Accumulation of neurofilaments has been observed in several forms of neurodegenerative diseases, but the mechanisms how elevated neurofilament levels d...

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Detalles Bibliográficos
Autores principales: Yadav, Preeti, Selvaraj, Bhuvaneish T., Bender, Florian L. P., Behringer, Marcus, Moradi, Mehri, Sivadasan, Rajeeve, Dombert, Benjamin, Blum, Robert, Asan, Esther, Sauer, Markus, Julien, Jean-Pierre, Sendtner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911381/
https://www.ncbi.nlm.nih.gov/pubmed/27021905
http://dx.doi.org/10.1007/s00401-016-1564-y