Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors

We previously reported the generation of integration-free induced pluripotent stem cells from adult peripheral blood (PB) with an improved episomal vector (EV) system, which uses the spleen focus-forming virus U3 promoter and an extra factor BCL-XL (B). Here we show an ∼100-fold increase in efficien...

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Detalles Bibliográficos
Autores principales: Wen, Wei, Zhang, Jian-Ping, Xu, Jing, Su, Ruijun Jeanna, Neises, Amanda, Ji, Guang-Zhen, Yuan, Weiping, Cheng, Tao, Zhang, Xiao-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911493/
https://www.ncbi.nlm.nih.gov/pubmed/27161365
http://dx.doi.org/10.1016/j.stemcr.2016.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911493/
https://www.ncbi.nlm.nih.gov/pubmed/27161365
http://dx.doi.org/10.1016/j.stemcr.2016.04.005

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