Highly potent intracellular membrane-associated Aβ seeds

An early event in Alzheimer’s disease (AD) pathogenesis is the formation of extracellular aggregates of amyloid-β peptide (Aβ), thought to be initiated by a prion-like seeding mechanism. However, the molecular nature and location of the Aβ seeds remain rather elusive. Active Aβ seeds are found in cr...

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Detalles Bibliográficos
Autores principales: Marzesco, Anne-Marie, Flötenmeyer, Matthias, Bühler, Anika, Obermüller, Ulrike, Staufenbiel, Matthias, Jucker, Mathias, Baumann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911570/
https://www.ncbi.nlm.nih.gov/pubmed/27311744
http://dx.doi.org/10.1038/srep28125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911570/
https://www.ncbi.nlm.nih.gov/pubmed/27311744
http://dx.doi.org/10.1038/srep28125

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