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A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer

Tumor-derived exosomes are important for cell-cell communication. However, the role of TP53 in the control of exosome production in colorectal cancer (CRC) is controversial and unclear. The features of exosomes secreted from HCT116 TP53-wild type (WT), TP53-knockout (KO) and constructed TP53 (R273H)...

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Detalles Bibliográficos
Autores principales: Sun, Yulin, Zheng, Weiwei, Guo, Zhengguang, Ju, Qiang, Zhu, Lin, Gao, Jiajia, Zhou, Lanping, Liu, Fang, Xu, Yang, Zhan, Qimin, Zhou, Zhixiang, Sun, Wei, Zhao, Xiaohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911576/
https://www.ncbi.nlm.nih.gov/pubmed/27312428
http://dx.doi.org/10.1038/srep28083