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A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging

In preclinical cancer research, bioluminescence imaging with firefly luciferase and D-luciferin has become a standard to monitor biological processes both in vitro and in vivo. However, the emission maximum (λ(max)) of bioluminescence produced by D-luciferin is 562 nm where light is not highly penet...

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Detalles Bibliográficos
Autores principales: Kuchimaru, Takahiro, Iwano, Satoshi, Kiyama, Masahiro, Mitsumata, Shun, Kadonosono, Tetsuya, Niwa, Haruki, Maki, Shojiro, Kizaka-Kondoh, Shinae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911627/
https://www.ncbi.nlm.nih.gov/pubmed/27297211
http://dx.doi.org/10.1038/ncomms11856