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A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
In preclinical cancer research, bioluminescence imaging with firefly luciferase and D-luciferin has become a standard to monitor biological processes both in vitro and in vivo. However, the emission maximum (λ(max)) of bioluminescence produced by D-luciferin is 562 nm where light is not highly penet...
Autores principales: | Kuchimaru, Takahiro, Iwano, Satoshi, Kiyama, Masahiro, Mitsumata, Shun, Kadonosono, Tetsuya, Niwa, Haruki, Maki, Shojiro, Kizaka-Kondoh, Shinae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911627/ https://www.ncbi.nlm.nih.gov/pubmed/27297211 http://dx.doi.org/10.1038/ncomms11856 |
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