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The PUF binding landscape in metazoan germ cells

PUF (Pumilio/FBF) proteins are RNA-binding proteins and conserved stem cell regulators. The Caenorhabditis elegans PUF proteins FBF-1 and FBF-2 (collectively FBF) regulate mRNAs in germ cells. Without FBF, adult germlines lose all stem cells. A major gap in our understanding of PUF proteins, includi...

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Detalles Bibliográficos
Autores principales: Prasad, Aman, Porter, Douglas F., Kroll-Conner, Peggy L., Mohanty, Ipsita, Ryan, Anne R., Crittenden, Sarah L., Wickens, Marvin, Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911911/
https://www.ncbi.nlm.nih.gov/pubmed/27165521
http://dx.doi.org/10.1261/rna.055871.116