Modeling and gene knockdown to assess the contribution of nonsense-mediated decay, premature termination, and selenocysteine insertion to the selenoprotein hierarchy

The expression of selenoproteins, a specific group of proteins that incorporates selenocysteine, is hierarchically regulated by the availability of Se, with some, but not all selenoprotein mRNA transcripts decreasing in abundance with decreasing Se. Selenocysteine insertion into the peptide chain oc...

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Detalles Bibliográficos
Autores principales: Zupanic, Anze, Meplan, Catherine, Huguenin, Grazielle V.B., Hesketh, John E., Shanley, Daryl P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911915/
https://www.ncbi.nlm.nih.gov/pubmed/27208313
http://dx.doi.org/10.1261/rna.055749.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911915/
https://www.ncbi.nlm.nih.gov/pubmed/27208313
http://dx.doi.org/10.1261/rna.055749.115

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