Sgs1's roles in DNA end resection, HJ dissolution, and crossover suppression require a two-step SUMO regulation dependent on Smc5/6

The RecQ helicase Sgs1 plays critical roles during DNA repair by homologous recombination, from end resection to Holliday junction (HJ) dissolution. Sgs1 has both pro- and anti-recombinogenic roles, and therefore its activity must be tightly regulated. However, the controls involved in recruitment a...

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Detalles Bibliográficos
Autores principales: Bermúdez-López, Marcelino, Villoria, María Teresa, Esteras, Miguel, Jarmuz, Adam, Torres-Rosell, Jordi, Clemente-Blanco, Andres, Aragon, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911932/
https://www.ncbi.nlm.nih.gov/pubmed/27298337
http://dx.doi.org/10.1101/gad.278275.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911932/
https://www.ncbi.nlm.nih.gov/pubmed/27298337
http://dx.doi.org/10.1101/gad.278275.116

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