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Dimethylarginine dimethylaminohydrolase-2 deficiency promotes vascular regeneration and attenuates pathological angiogenesis

Ischemia-induced angiogenesis is critical for tissue repair, but aberrant neovascularization in the retina causes severe sight impairment. Nitric oxide (NO) has been implicated in neovascular eye disease because of its pro-angiogenic properties in the retina. Nitric oxide production is inhibited end...

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Detalles Bibliográficos
Autores principales: Lange, Clemens, Mowat, Freya, Sayed, Haroon, Mehad, Manjit, Duluc, Lucie, Piper, Sophie, Luhmann, Ulrich, Nandi, Manasi, Kelly, Peter, Smith, Alexander, Ali, Robin, Leiper, James, Bainbridge, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912010/
https://www.ncbi.nlm.nih.gov/pubmed/27181226
http://dx.doi.org/10.1016/j.exer.2016.05.007