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In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

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Detalles Bibliográficos
Autores principales: Wongthida, Phonphimon, Jengarn, Juggragarn, Narkpuk, Jaraspim, Koonyosying, Pongpisid, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Leaungwutiwong, Pornsawan, Teeravechyan, Samaporn, Jongkaewwattana, Anan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912100/
https://www.ncbi.nlm.nih.gov/pubmed/27315286
http://dx.doi.org/10.1371/journal.pone.0157287