Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism

The parasite Leishmania often relies on gene rearrangements to survive stressful environments. However, safeguarding a minimum level of genome integrity is important for cell survival. We hypothesized that maintenance of genomic integrity in Leishmania would imply a leading role of the MRE11 and RAD...

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Detalles Bibliográficos
Autores principales: Laffitte, Marie-Claude N., Leprohon, Philippe, Hainse, Maripier, Légaré, Danielle, Masson, Jean-Yves, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912120/
https://www.ncbi.nlm.nih.gov/pubmed/27314941
http://dx.doi.org/10.1371/journal.pgen.1006117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912120/
https://www.ncbi.nlm.nih.gov/pubmed/27314941
http://dx.doi.org/10.1371/journal.pgen.1006117

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