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Genetic Association Analysis Reveals Differences in the Contribution of NOD2 Variants to the Clinical Phenotypes of Orofacial Granulomatosis

BACKGROUND: Orofacial granulomatosis (OFG) is a rare, inflammatory disorder of the mouth, in which some patients also have intestinal Crohn's disease (CD). The etiology remains largely unknown, although there is a high prevalence of atopy, and oral granulomas are also seen in other immune disor...

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Detalles Bibliográficos
Autores principales: Mentzer, Alexander, Nayee, Shalini, Omar, Yasmin, Hullah, Esther, Taylor, Kirstin, Goel, Rishi, Bye, Hannah, Shembesh, Tarik, Elliott, Timothy R., Campbell, Helen, Patel, Pritash, Nolan, Anita, Mansfield, John, Challacombe, Stephen, Escudier, Michael, Mathew, Christopher G., Sanderson, Jeremy D., Prescott, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912233/
https://www.ncbi.nlm.nih.gov/pubmed/27306066
http://dx.doi.org/10.1097/MIB.0000000000000844