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Increased expression of Tbet in CD4(+) T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS

BACKGROUND: The ability to identify clinically isolated syndrome (CIS) patients at high risk of progression to clinically definite multiple sclerosis (CDMS) would be clinically beneficial. The initiation of T cell mediated autoimmune diseases such as multiple sclerosis (MS) requires the initial inap...

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Detalles Bibliográficos
Autores principales: Basdeo, Sharee A., Kelly, Siobhan, O’Connell, Karen, Tubridy, Niall, McGuigan, Christopher, Fletcher, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912535/
https://www.ncbi.nlm.nih.gov/pubmed/27386265
http://dx.doi.org/10.1186/s40064-016-2510-0