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Robust estimates of overall immune-repertoire diversity from high-throughput measurements on samples
The diversity of an organism's B- and T-cell repertoires is both clinically important and a key measure of immunological complexity. However, diversity is hard to estimate by current methods, because of inherent uncertainty in the number of B- and T-cell clones that will be missing from a blood...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912625/ https://www.ncbi.nlm.nih.gov/pubmed/27302887 http://dx.doi.org/10.1038/ncomms11881 |